Targeting LIF-mediated paracrine communication for pancreatic cancer therapy. Yu Shi, Weina Gao, Nikki K Lytle, Peiwu Huang, Xiao Yuan, Amanda M Dann, Maya Ridinger-Saison, Kathleen E DelGiorno, Corina E Antal, Gaoyang Liang, Annette R Atkins, Galina Erikson, Huaiyu Sun, Jill Meisenhelder, Elena Terenziani, Gyunghwi Woo, Linjing Fang, Thom P Santisakultarm, Uri Manor, Ruilian Xu, Carlos […]
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. Nikki K. Lytle; L. Paige Ferguson; Nirakar Rajbhandari; Kathryn Gilroy; Raymond G. Fox; Anagha Deshpande; Christian M. Schürch, Michael Hamilton; Neil Robertson; Wei Lin; Pawan Noel; Martin Wartenberg; Inti Zlobec; Micha Eichmann; José A. Galván; Eva Karamitopoulou; Tami Gilderman; Lourdes Adriana Esparza; Yutaka Shima; […]
Glucose feeds the TCA cycle via circulating lactate. Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo, Eileen White and Joshua D Rabinowitz. Nature. 2017 Nov 2;551(7678):115-118. doi: 10.1038/nature24057. PDF |
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma Raymond G. Fox, Nikki K. Lytle, Dawn V. Jaquish, Frederick D. Park, Takahiro Ito, Jeevisha Bajaj, Claire S. Koechlein, Bryan Zimdahl, Masato Yano, Janel L. Kopp, Marcie Kritzik, Jason K. Sicklick, Maike Sander, Paul M. Grandgenett, Michael A. Hollingsworth, Shinsuke Shibata, Donald Pizzo, Mark A. […]
CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia. Bajaj J, Konuma T, Lytle NK, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van der Horst EH, Ginsberg MH, Reya T. Cancer Cell. 2016 Nov 14;30(5):792-805. DOI: 10.1016/j.ccell.2016.10.003. PubMed | PDF |
High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo. Claire S. Koechlein, Jeffrey R. Harris, Timothy Lee, Joi Weeks, Raymond G. Fox, Bryan Zimdahl, Takahiro Ito, Allen Blevins, Seung-Hye Jung, John P. Chute, Amit Chourasia, Markus Covert and Tannishtha Reya. 2016. Nature Communications DOI:10.1038/ncomms12169. PubMed | PDF |
Delayed onset of symptoms through feedback interference in chronic cancers. Haney S, Reya T and Bazhenov M. Convergent Science Physical Oncology 2016;2(4):045002. doi: 10.1088/2057-1739/2/4/045002. PubMed | PDF |
Musashi Signaling in Stem Cells and Cancer Raymond G. Fox, Frederick D. Park, Claire S. Koechlein, Marcie Kritzik, and Tannishtha Reya. 2015. The Annual Review of Cell and Developmental Biology DOI: 10.1146/annurev-cellbio-100814-125446. PubMed | PDF |
Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia Hyog Young Kwon, Jeevisha Bajaj, Takahiro Ito, Allen Blevins, Takaaki Konuma, Joi Weeks, Nikki K. Lytle, Claire S. Koechlein, David Rizzieri, Charles Chuah, Vivian G. Oehler, Roman Sasik, Gary Hardiman, Tannishtha Reya. 2015. Cell Stem Cell DOI: 10.1016/j.stem.2015.06.006. PubMed | PDF |
Fearful Symmetry: Subversion of Asymmetric Division in Cancer Development and Progression Jeevisha Bajaj, Bryan Zimdahl, and Tannishtha Reya. 2015. Cancer Research DOI: 10.1158/0008-5472.CAN-14-2750. PubMed | PDF |
