A closer look at the single cell. Megan Scudellari. Nature Reports Stem Cells. 2009. – Reya Lab

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A closer look at the single cell. Megan Scudellari. Nature Reports Stem Cells. 2009.

Publications

Regulation of lung cancer initiation and progression by the stem cell determinant Musashi2025 -
Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia2024 -
Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer2023 -
Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma2023 -
The role of the microenvironment and immune system in regulating stem cell fate in cancer.2021 -
AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth.2021 -
A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia.2020 -
MARCH proteins mediate responses to antitumor antibodies.2020 -
Genomic landscape and therapeutic targets of adenosquamous carcinoma of the pancreas.2020 -
An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.2020 -
Stem Cells in Cancer Initiation and Progression.2020 -
Targeting LIF-mediated paracrine communication for pancreatic cancer therapy.2019 -
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma2019 -
Stem cell fate in cancer growth, progression and therapy resistance.2018 -
Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity.2018 -
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas2018 -
Glucose feeds the TCA cycle via circulating lactate.2017 -
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma2016 -
CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia2016 -
High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo.2016 -

Tannishtha Reya
Professor
Physiology and Cellular Biophysics
Herbert Irving Comprehensive Cancer Center
Columbia University, New York, NY 10032
tr2726@cumc.columbia.edu

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Born in the Blood. Kathleen Yount. Duke Med Magazine. 2009.Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid...