Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity.
Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity.
Dravis C, Chung C, Lytle NK, Herrera-Valdez J, Luna G, Trejo CL, Reya T, Wahl GM.
Cancer Cell. 2018 Sep 10;34(3):466-482.e6. DOI: 10.1016/j.ccell.2018.08.001. PubMed | PDF | Read more
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.
Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle NK, Dhar D, Banerjee S, Fagman JB, Browne CD, Umemura A, Valasek MA, Kessler H, Tarin D, Goggins M, Reya T, Diaz-Meco M, Moscat J, Karin M.
Cancer Cell. 2017 Dec 11;32(6):824-839.e8. DOI: 10.1016/j.ccell.2017.10.011. PubMed | PDF | Read more
Glucose feeds the TCA cycle via circulating lactate.
Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo, Eileen White and Joshua D Rabinowitz.
Nature. 2017 Nov 2;551(7678):115-118. doi: 10.1038/nature24057. PDF | Read more
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma
Raymond G. Fox, Nikki K. Lytle, Dawn V. Jaquish, Frederick D. Park, Takahiro Ito, Jeevisha Bajaj, Claire S. Koechlein, Bryan Zimdahl, Masato Yano, Janel L. Kopp, Marcie Kritzik, Jason K. Sicklick, Maike Sander, Paul M. Grandgenett, Michael A. Hollingsworth, Shinsuke Shibata, Donald Pizzo, Mark A. Valasek, Roman Sasik, Miriam Scadeng, Hideyuki Okano, Youngsoo Kim, A. Robert MacLeod, Andrew M. Lowy & Tannishtha Reya. 2016.
Nature DOI: 10.1038/nature17988. PubMed | PDF | Read more
CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia
CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia.
Bajaj J, Konuma T, Lytle NK, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van der Horst EH, Ginsberg MH, Reya T.
Cancer Cell. 2016 Nov 14;30(5):792-805. DOI: 10.1016/j.ccell.2016.10.003. PubMed | PDF | Read more
High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo.
High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo.
Claire S. Koechlein, Jeffrey R. Harris, Timothy Lee, Joi Weeks, Raymond G. Fox, Bryan Zimdahl, Takahiro Ito, Allen Blevins, Seung-Hye Jung, John P. Chute, Amit Chourasia, Markus Covert and Tannishtha Reya. 2016.
Nature Communications DOI:10.1038/ncomms12169. PubMed | PDF | Read more
Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia
Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia
Hyog Young Kwon, Jeevisha Bajaj, Takahiro Ito, Allen Blevins, Takaaki Konuma, Joi Weeks, Nikki K. Lytle, Claire S. Koechlein, David Rizzieri, Charles Chuah, Vivian G. Oehler, Roman Sasik, Gary Hardiman, Tannishtha Reya. 2015.
Cell Stem Cell DOI: 10.1016/j.stem.2015.06.006. PubMed | PDF | Read more
Tannishtha Reya
Professor
Physiology and Cellular Biophysics
Herbert Irving Comprehensive Cancer Center
Columbia University, New York, NY 10032
tr2726@cumc.columbia.edu
