Regulation of lung cancer initiation and progression by the stem cell determinant Musashi
eLife. 6 March 2025. https://doi.org/10.1101/2023.12.29.573601. PDF | Read more
Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer
Cancer Cell. 5 October 2023. doi: 10.1016/j.ccell.2023.09.008. Online ahead of print. PDF | Read more
Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma
L. Paige Ferguson, Jovylyn Gatchalian, Matthew L. McDermott, Mari Nakamura, Kendall Chambers, Nirakar Rajbhandari, Nikki K. Lytle, Sara Brin Rosenthal, Michael Hamilton, Sonia Albini, Martin Wartenberg, Inti Zlobec, José A. Galván, Eva Karamitopoulou, Vera Vavinskaya, Alexis Wascher, Andrew M. Lowy, Christian M. Schürch, Pier Lorenzo Puri, Benoit G. Bruneau, Diana C. Hargreaves & Tannishtha Reya .
Nature Communications. 3 January 2023. doi: 10.1038/s41467-023-35796-7. Online ahead of print. PDF | Read more
AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth.
Ita Novita Sari, Ying-Gui Yang, Yoseph Toni Wijaya, Nayoung Jun, Sanghyun Lee, Kwang Seock Kim, Jeevisha Bajaj, Vivian G Oehler, Soo-Hyun Kim, Soo-Young Choi, Sa-Hee Park, Dong-Wook Kim, Tannishtha Reya, Jaeseok Han and Hyog Young Kwon.
Oncogene. 2021 Jan;40(3):603-617. doi: 10.1038/s41388-020-01547-x. Epub 2020 Nov 17. PubMed | Read more
A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia.
Kyle Spinler, Jeevisha Bajaj, Takahiro Ito, Bryan Zimdahl, Michael Hamilton, Armin Ahmadi, Claire S. Koechlein, Nikki K Lytle, Hyog Young Kwon, Ferdous Anower-E-Khuda, Hao Sun, Allen Blevins, Joi Weeks, Marcie Kritzik, Jan Karlseder, Mark H. Ginsberg, Pyong Woo Park, Jeffrey D. Esko, and Tannishtha Reya.
Nature Communications. 2020 Nov 26;11(1):5998. doi: 10.1038/s41467-020-19782-x. PubMed | PDF | Read more
Genomic landscape and therapeutic targets of adenosquamous carcinoma of the pancreas.
Elizabeth Lenkiewicz, Smriti Malasi, Tara L. Hogenson, Luis F. Flores, Whitney Barham , William J. Phillips, Alexander S. Roesler, Kendall R. Chambers, Nirakar Rajbhandari, Akimasa Hayashi, Corina E. Antal, Michael Downes, Paul M Grandgenett, Michael A Hollingsworth, Derek Cridebring, Yuning Xiong, Jeong-Heon Lee, Zhenqing Ye, Huihuang Yan, Matthew C Hernandez, Jennifer L Leiting, Tamas Ordog, Mark J Truty, Mitesh J Borad, Tannishtha Reya, Daniel D Von Hoff, Martin E Fernandez-Zapico and Michael T Barrett.
Cancer Research. 2020 Oct 15;80(20):4324-4334. doi: 10.1158/0008-5472.CAN-20-0078. PubMed | PDF |
An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.
Jeevisha Bajaj, Michael Hamilton, Yutaka Shima, Kendall Chambers, Kyle Spinler, Eric L. Van Nostrand, Brian A. Yee, Steven M. Blue, Michael Chen, David Rizzeri, Charles Chuah, Vivian G. Oehler, H. Elizabeth Broome, Roman Sasik, James Scott-Browne, Anjana Rao, Gene W. Yeo and Tannishtha Reya. 2020
Nature Cancer. 1, 410–422 PDF | Read more
